Anti radiation drugs - The mechanisms of anti-radiation action: The optimal condition of protective action: Antioxidan: Enzyme and non-enzyme anti-radical effect, activation of Nrf2/KeapI and Sirtuin/FoxO pathway: Low-dose-rate irradiation, repeated prophylactic dose of drugs and nutrient supplement: Pro-oxidant

 
Oct 13, 2022 · A n announcement that the Department of Health and Human Services spent $290 million on a drug used to treat radiation sickness earlier this month raised eyebrows amid an uptick in nuclear threats ... . Shop bonfiglioli

Radiation protection, also known as radiological protection, is defined by the International Atomic Energy Agency (IAEA) as "The protection of people from harmful effects of exposure to ionizing radiation, and the means for achieving this". [1] Exposure can be from a source of radiation external to the human body or due to internal irradiation ... However, amifostine, developed by the U.S. Army Anti-Radiation Drug Development Program, is the only chemical radioprotector currently approved by the FDA. Amifostine has disadvantages such as limited administration routes, narrow administration window for efficacy, high cost, and limited protection of organs (Cheki et al. 2016 ).Cleveland Biolabs, a clinical-stage biotechnology company based out of Buffalo, NY (CBLI) with subsidiaries in Russia (covered later), has developed an anti-radiation drug CBLB502 (now known as ...From what I've seen, the effects of the anti-rad drugs seem to both remove any current radiation, and hold-off the effects of radiation for a few seconds. So basically: Walk towards radiation>Inject anti-rad>RUN LIKE HELL to get through> Use more anti-rad drugs if needed. HTC Vive.The global anti-radiation drugs market was valued at US$ 3.4 Bn in 2021 and is anticipated to grow at a CAGR of 9.9% from 2022 to 2031. Increase in demand for drugs, such as Prussian Blue ...Prussian blue side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Prussian blue may cause serious side effects. Call your doctor at once if you have: severe constipation; or. severe stomach pain.Nplate is also approved for adult and pediatric patients with immune thrombocytopenia, a blood disorder resulting in low platelet counts. Repurposing drugs for acute radiation syndrome that also are approved for a commercial indication helps to sustain availability of the product and improves healthcare provider familiarity with the drug.Since 2008, the official body has invested $164m into anti-radiation drug candidates. Countermeasures against ARS under development in companies and funded by federal programmes currently range from stem cell treatments to toll-like receptor agonists. The Maryland-based stem cell company Osiris Therapeutics has recently received a contract from ...Oct 6, 2022 · A radiation warning sign near the ghost town of Pripyat not far from Chernobyl in 2017 in Ukraine. The Biden Administration purchased $290 million worth of a nuclear emergency drug administered by subcutaneous injection amid escalating nuclear brinkmanship between the Russian Federation and NATO. (Image: Sean Gallup/Getty Images) KI will not provide protection from any type of radiation exposure other than radioactive Iodine. KI should not be taken simply because there is a public notification of a radiation emergency. DHEC public health officials will advise the public when it is appropriate to consume the drug; based on whether radioactive Iodine is being released.Wilmington, Delaware, United States, Aug. 11, 2023 (GLOBE NEWSWIRE) -- The global anti-radiation drugs market is projected to flourish at a CAGR of 9.9% from 2022 to 2031.Aug 7, 2014 · The mechanisms of anti-radiation action: The optimal condition of protective action: Antioxidan: Enzyme and non-enzyme anti-radical effect, activation of Nrf2/KeapI and Sirtuin/FoxO pathway: Low-dose-rate irradiation, repeated prophylactic dose of drugs and nutrient supplement: Pro-oxidant At the federal government's request, they cranked up a production line in Illinois at 3 a.m., and hours later, thousands of bottles of potassium iodide, an anti-radiation drug, were secretly ...Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach to treating many types of cancer. In RPT, radiation is systemically or locally delivered using ...Oct. 7, 2022, 1:16 PM PDT By Berkeley Lovelace Jr. Amid concerns about Russian President Vladimir Putin’s recent nuclear threats came a bit of startling news: The U.S. Department of Health and...Antineoplastic drugs used to shrink cancer cells before radiation therapy. Adjuvant chemotherapy. Chemotherapy administered after other treatments to shrink remaining cancer cells.The US spent $290 million on anti-radiation pills to save lives after a "nuclear emergency". The US Department for Health and Human Services said the purchase was part of a "long-standing program" The drug can be used to treat adults and children. Nplate is also approved for adult and pediatric patients with immune thrombocytopenia, a blood disorder resulting in low platelet counts. Repurposing drugs for acute radiation syndrome that also are approved for a commercial indication helps to sustain availability of the product and improves ...Prussian blue traps radioactive cesium and thallium in the intestines to keep them from being absorbed by the body. These radioactive materials move through the intestines and pass out of the body (excrete) in bowel movements. Getting these materials out of the body help limit the amount of time they expose the body to radiation.Since 2008, the official body has invested $164m into anti-radiation drug candidates. Countermeasures against ARS under development in companies and funded by federal programmes currently range from stem cell treatments to toll-like receptor agonists. The Maryland-based stem cell company Osiris Therapeutics has recently received a contract from ...KI can cause harmful health effects when not taken exactly as directed by a healthcare provider or public health official. Taking more KI than recommended can cause severe illness or death. Some people have harmful health effects, like gastrointestinal upset, rashes, or allergic reactions from KI even when taken correctly. Top of Page.Authored by Chris Menahan via InformationLiberation.com, The Biden regime is buying up $290 million in anti-radiation drugs for use in "nuclear emergencies" amid escalating tensions with Russia and heightened threats of a nuclear war.Serotonin (5-HT3) antagonists block the effects of serotonin, a substance that commonly triggers nausea and vomiting. These drugs are effective at controlling acute nausea and vomiting and are usually given before chemo and then for a few days afterward. (Examples: ondansetron, granisetron, dolasetron, palonosetron)Jul 14, 2023 · The global Anti-radiation Drugs market is estimated to attain a valuation of US$ 9.6 Bn by the end of 2031, states a study by Transparency Market Research (TMR). Besides, the report notes that the market is prognosticated to expand at a CAGR of 9.9% during the forecast period, 2022-2031. The key objective of the TMR report is… Aug 11, 2023 · Wilmington, Delaware, United States, Aug. 11, 2023 (GLOBE NEWSWIRE) -- The global anti-radiation drugs market is projected to flourish at a CAGR of 9.9% from 2022 to 2031. As per the report ... Feb 15, 2021 · We aimed at establishing novel therapeutic avenues for the development and clinical applications of radiation protective drugs. Anti-Radiation Active Compounds of Chinese Herbal Medicines. Active compounds in Chinese herbal medicines can scavenge for free radicals, reduce DNA damage, promote post-injury repair, and reduce cell apoptosis. Jul 14, 2023 · The global Anti-radiation Drugs market is estimated to attain a valuation of US$ 9.6 Bn by the end of 2031, states a study by Transparency Market Research (TMR). Besides, the report notes that the market is prognosticated to expand at a CAGR of 9.9% during the forecast period, 2022-2031. The key objective of the TMR report is… The Biden administration has placed an order for $290 million worth of a drug that can be used to treat radiation sickness. On October 4, the United States Department for Health and Human Services ...20 Minutes in the Future, medical advances will bring us anti-rad drugs — special substances made for the purpose of treating the harmful effects of radiation on the human body. Whether they are called Rad-X, Rad-Away, hyronalin, Neutrad, or just Anti-Rad, these drugs usually fall into two main categories: Preventative anti-rad drugs, meant ... Delayed dose. Although there are no approved anti-radiation drugs on the market, a number of other therapies are in development, but most must be given within about 24 hours of exposure. “A drug ...Radiation sickness agents treat the symptoms of Acute Radiation Sickness. This includes medications to treat a gastrointestinal injury and its symptoms, nausea and vomiting, and diarrhea. This category might include antibiotics to treat opportunistic infections from the impact of reduced white blood cells. HHS Spends $290 Million On Extra Radiation Sickness Medication. It could be a "troubling sign of the times," FiercePharma says, noting the money is buying an "undisclosed" amount of the Amgen drug Nplate — approved to treat blood cell injuries from acute radiation sickness. The Department of Health and Human Services downplayed the purchase.Nplate is also approved for adult and pediatric patients with immune thrombocytopenia, a blood disorder resulting in low platelet counts. Repurposing drugs for acute radiation syndrome that also are approved for a commercial indication helps to sustain availability of the product and improves healthcare provider familiarity with the drug.These treatments include the following: Potassium iodide (ThyroShield, Iosat). This is a nonradioactive form of iodine. Iodine is essential for proper thyroid... Prussian blue (Radiogardase). This type of dye binds to particles of radioactive elements known as cesium and thallium. Diethylenetriamine ...According to the latest anti-radiation drugs market trends, the Acute Radiation Syndrome (ARS) application segment accounted for the largest share of the global anti-radiation drugs business in 2021. ARS is one of the most challenging aspects of public health and medical response to a nuclear or radiological incident.4. Glutathione. Glutathione, a water-soluble antioxidant available in supplement and tincture form, is essential in protecting cells from damage caused by free radicals and heavy metals. Beyond its role in cellular defense, glutathione may also help counteract the detrimental effects of EMF radiation.The sulfonamide pharmacophore has been used as a drug since the 1930s and is a current component of well over 100 approved drugs with anti-bacterial, anti-cancer, anti-carbonic anhydrase, anti-diabetic, anti-protease, anti-inflammatory, and many other activities (Supuran, 2017); to which radiationThe sulfonamide pharmacophore has been used as a drug since the 1930s and is a current component of well over 100 approved drugs with anti-bacterial, anti-cancer, anti-carbonic anhydrase, anti-diabetic, anti-protease, anti-inflammatory, and many other activities (Supuran, 2017); to which radiationOct 6, 2022 · AP Photo, File. The U.S. Department of Health and Human Services (HHS) announced this week that the Biden administration agency has procured $290 million worth of a drug used to counter negative ... The Biden administration has placed an order for $290 million worth of a drug that can be used to treat radiation sickness. On October 4, the United States Department for Health and Human Services ...Wilmington, Delaware, United States, Aug. 11, 2023 (GLOBE NEWSWIRE) -- The global anti-radiation drugs market is projected to flourish at a CAGR of 9.9% from 2022 to 2031. As per the report ...Oct 25, 2018 · However, amifostine, developed by the U.S. Army Anti-Radiation Drug Development Program, is the only chemical radioprotector currently approved by the FDA. Amifostine has disadvantages such as limited administration routes, narrow administration window for efficacy, high cost, and limited protection of organs (Cheki et al. 2016 ). Nov 5, 2021 · Inflammation-related cytokines are another high-frequency group of anti-radiation drugs for digestive injury. IL-6-related anti-radiation drugs include ciprofloxacin , C-GSF , 18-β-glycyrrhetinic acid , CD28 mimetic peptide p2TA , delta-tocotrienol , and palmitoylethanolamide , suggesting that inflammatory inhibitors may also contribute to ... The Biden administration has placed an order for $290 million worth of a drug that can be used to treat radiation sickness. On October 4, the United States Department for Health and Human Services ...Oct 25, 2018 · However, amifostine, developed by the U.S. Army Anti-Radiation Drug Development Program, is the only chemical radioprotector currently approved by the FDA. Amifostine has disadvantages such as limited administration routes, narrow administration window for efficacy, high cost, and limited protection of organs (Cheki et al. 2016 ). The US spent $290 million on anti-radiation pills to save lives after a "nuclear emergency". The US Department for Health and Human Services said the purchase was part of a "long-standing program" Sep 17, 2012 · Cleveland Biolabs, a clinical-stage biotechnology company based out of Buffalo, NY (CBLI) with subsidiaries in Russia (covered later), has developed an anti-radiation drug CBLB502 (now known as ... But radiation health experts say the pills aren't really helpful in the aftermath of a nuclear attack. ... Jones said he sent out about 140,000 doses of the drug, whereas he normally would have ...From what I've seen, the effects of the anti-rad drugs seem to both remove any current radiation, and hold-off the effects of radiation for a few seconds. So basically: Walk towards radiation>Inject anti-rad>RUN LIKE HELL to get through> Use more anti-rad drugs if needed. HTC Vive.The U.S. government just dropped $290 million dollars on anti-radiation drugs in the wake of escalated nuclear rhetoric from Russian President Vladimir Putin; procurement of the drug Nplate, to treat acute radiation syndrome (ARS), was announced by the US Health and Human Services (HSS).May 16, 2011 · Since 2008, the official body has invested $164m into anti-radiation drug candidates. Countermeasures against ARS under development in companies and funded by federal programmes currently range from stem cell treatments to toll-like receptor agonists. The Maryland-based stem cell company Osiris Therapeutics has recently received a contract from ... In physics, radiation is the emission or transmission of energy in the form of waves or particles through space or through a material medium. This includes: electromagnetic radiation, such as radio waves, microwaves, infrared, visible light, ultraviolet, x-rays, and gamma radiation (γ) particle radiation, such as alpha radiation (α), beta ... Aug 11, 2023 · Wilmington, Delaware, United States, Aug. 11, 2023 (GLOBE NEWSWIRE) -- The global anti-radiation drugs market is projected to flourish at a CAGR of 9.9% from 2022 to 2031. As per the report ... Oct 6, 2022 · HHS Spends $290 Million On Extra Radiation Sickness Medication. It could be a "troubling sign of the times," FiercePharma says, noting the money is buying an "undisclosed" amount of the Amgen drug Nplate — approved to treat blood cell injuries from acute radiation sickness. The Department of Health and Human Services downplayed the purchase. October 07, 2022 Elizabeth Lawrence. President Joe Biden’s administration purchased $290 million of anti-radiation medication this week amid threats of nuclear war repeatedly issued by Russian President Vladimir Putin. Biden also warned this week that “the prospect of [nuclear] Armageddon” is real and Putin was “not joking when he talks ...KI Is Not an “Anti-Radiation” Drug. Radioactive iodine contamination is mainly associated with nuclear power plant accidents. In other types of nuclear emergencies, such as a nuclear detonation, the biggest risk is external exposure to many types of radioactive materials. It is best to shelter in place for protection. Learn More Poland discusses hosting American nuclear weapons as US buys up anti-radiation drugs. ... medical countermeasures available in case a catastrophic event exposes people to high doses of radiation ...Oct 7, 2022 · Acute radiation syndrome occurs when a person's "entire body is exposed to a high dose of penetrating radiation" — the kind resulting from a nuclear explosion or a dirty bomb. Nplate serves to reduce radiation-induced bleeding by stimulating the body's production of platelets. The drug can reportedly be used in both adults and children. Nplate is also approved for adult and pediatric patients with immune thrombocytopenia, a blood disorder resulting in low platelet counts. Repurposing drugs for acute radiation syndrome that also are approved for a commercial indication helps to sustain availability of the product and improves healthcare provider familiarity with the drug.The US spent $290 million on anti-radiation pills to save lives after a "nuclear emergency". The US Department for Health and Human Services said the purchase was part of a "long-standing program"But radiation health experts say the pills aren't really helpful in the aftermath of a nuclear attack. ... Jones said he sent out about 140,000 doses of the drug, whereas he normally would have ...Jan 27, 2023 · WHO recommends stockpiling radiation drugs in case of ‘nuclear emergency’. The explosion and mushroom cloud resulting from the Trinity nuclear explosion. (U.S. Department of Energy/Released) The World Health Organization (WHO) updated its list of recommended drugs to stockpile for nuclear emergencies on Friday for the first time since 2007. KI Is Not an “Anti-Radiation” Drug. Radioactive iodine contamination is mainly associated with nuclear power plant accidents. In other types of nuclear emergencies, such as a nuclear detonation, the biggest risk is external exposure to many types of radioactive materials. It is best to shelter in place for protection. Learn MoreOct 6, 2022 · The Department of Health and Human Services (HHS) says it has spent $290 million on a drug to treat radiation sickness in the event of a nuclear emergency. The HHS Administration for Strategic ... Compare risks and benefits of common medications used for Radiation Emergency. Find the most ... Aside from radiation sickness caused by nuclear attacks or accidents, anti-radiation drugs could have applications for people receiving radiation therapy for cancer, those with weakened...The US spent $290 million on anti-radiation pills to save lives after a "nuclear emergency". The US Department for Health and Human Services said the purchase was part of a "long-standing program"Oct 7, 2022 · The U.S. government this week bought $290 million in supplies of a drug designed to treat blood cell injuries following radiological and nuclear emergencies as part of what it said were long ... Wilmington, Delaware, United States, Aug. 11, 2023 (GLOBE NEWSWIRE) -- The global anti-radiation drugs market is projected to flourish at a CAGR of 9.9% from 2022 to 2031. As per the report ...Nplate is also approved for adult and pediatric patients with immune thrombocytopenia, a blood disorder resulting in low platelet counts. Repurposing drugs for acute radiation syndrome that also are approved for a commercial indication helps to sustain availability of the product and improves healthcare provider familiarity with the drug.According to the latest anti-radiation drugs market trends, the Acute Radiation Syndrome (ARS) application segment accounted for the largest share of the global anti-radiation drugs business in 2021. ARS is one of the most challenging aspects of public health and medical response to a nuclear or radiological incident. According to the dose reduction factor, the expected radiation protective effect of the radioprotector for humans is up to 1.5. The drug betaleukin (recombinant human IL-1β) proposed as agent of early urgent anti-radiation therapy applying within two hours after irradiation. Two drugs can block the deadly effects of radiation poisoning in mice when given up to 24 hours after exposure. The finding points to a possible new way to protect against radiation injury from environmental exposures or cancer therapy. High doses of radiation—whether from medical therapy or a large-scale nuclear emergency—can harm the body ...The US just spent $290 million on anti-radiation pills used to "save lives following radiation and nuclear emergencies". The US Department for Health and Human Services (HHS) announced Tuesday it ... Jul 20, 2023 · Prussian blue side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Prussian blue may cause serious side effects. Call your doctor at once if you have: severe constipation; or. severe stomach pain. Inflammation-related cytokines are another high-frequency group of anti-radiation drugs for digestive injury. IL-6-related anti-radiation drugs include ciprofloxacin , C-GSF , 18-β-glycyrrhetinic acid , CD28 mimetic peptide p2TA , delta-tocotrienol , and palmitoylethanolamide , suggesting that inflammatory inhibitors may also contribute to ...Authored by Chris Menahan via InformationLiberation.com, The Biden regime is buying up $290 million in anti-radiation drugs for use in "nuclear emergencies" amid escalating tensions with Russia and heightened threats of a nuclear war.A radiation warning sign near the ghost town of Pripyat not far from Chernobyl in 2017 in Ukraine. The Biden Administration purchased $290 million worth of a nuclear emergency drug administered by subcutaneous injection amid escalating nuclear brinkmanship between the Russian Federation and NATO. (Image: Sean Gallup/Getty Images)In physics, radiation is the emission or transmission of energy in the form of waves or particles through space or through a material medium. This includes: electromagnetic radiation, such as radio waves, microwaves, infrared, visible light, ultraviolet, x-rays, and gamma radiation (γ) particle radiation, such as alpha radiation (α), beta ...20 Minutes in the Future, medical advances will bring us anti-rad drugs — special substances made for the purpose of treating the harmful effects of radiation on the human body. Whether they are called Rad-X, Rad-Away, hyronalin, Neutrad, or just Anti-Rad, these drugs usually fall into two main categories: Preventative anti-rad drugs, meant ... Aug 11, 2023 · Wilmington, Delaware, United States, Aug. 11, 2023 (GLOBE NEWSWIRE) -- The global anti-radiation drugs market is projected to flourish at a CAGR of 9.9% from 2022 to 2031. May 16, 2011 · Since 2008, the official body has invested $164m into anti-radiation drug candidates. Countermeasures against ARS under development in companies and funded by federal programmes currently range from stem cell treatments to toll-like receptor agonists. The Maryland-based stem cell company Osiris Therapeutics has recently received a contract from ... Treatment for internal contamination. Potassium iodide (ThyroShield, Iosat). This is a nonradioactive form of iodine. Prussian blue (Radiogardase). This type of dye binds to particles of radioactive elements known as cesium and thallium. The radioactive particles are ... Diethylenetriamine ... KI will not provide protection from any type of radiation exposure other than radioactive Iodine. KI should not be taken simply because there is a public notification of a radiation emergency. DHEC public health officials will advise the public when it is appropriate to consume the drug; based on whether radioactive Iodine is being released.Wilmington, Delaware, United States, Aug. 11, 2023 (GLOBE NEWSWIRE) -- The global anti-radiation drugs market is projected to flourish at a CAGR of 9.9% from 2022 to 2031. As per the report ...Aug 11, 2023 · The global anti-radiation drugs market is projected to flourish at a CAGR of 9.9% from 2022 to 2031. As per the report published by TMR, a valuation of US$ 9.6 A $290 million procurement of the drug Nplate, to treat acute radiation syndrome (ARS), was announced by the US Health and Human Services (HSS). ... US splashes $290m on anti-radiation drugs after ...The drug was approved by the FDA in January 2021 for use in people suffering from acute radiation syndrome following "a nuclear explosion, an accident at a nuclear reactor, a radiotherapy accident ...

The Department of Health and Human Services (HHS) says it has spent $290 million on a drug to treat radiation sickness in the event of a nuclear emergency. The HHS Administration for Strategic .... Is cefdinir used to treat covid 19

anti radiation drugs

Delayed dose. Although there are no approved anti-radiation drugs on the market, a number of other therapies are in development, but most must be given within about 24 hours of exposure. “A drug ...Dec 13, 2022 · The global anti-radiation drugs market was valued at US$ 3.4 Bn in 2021 and is anticipated to grow at a CAGR of 9.9% from 2022 to 2031. Increase in demand for drugs, such as Prussian Blue ... Prussian blue traps radioactive cesium and thallium in the intestines to keep them from being absorbed by the body. These radioactive materials move through the intestines and pass out of the body (excrete) in bowel movements. Getting these materials out of the body help limit the amount of time they expose the body to radiation. Abstract Anti-aging properties can be found in many compounds with radiation-protective effects. Such compounds include the following: bioflavonoids, some antioxidants (N-acetylcysteine), melatonin, some non-steroid anti-inflammatory agents and statins, angiotensin converting enzyme inhibitors, metformin, rapamycin, etc. The effects of the drugs can develop both in the case of their long-term ...Oct 6, 2022 · Nplate is also approved for adult and pediatric patients with immune thrombocytopenia, a blood disorder resulting in low platelet counts. Repurposing drugs for acute radiation syndrome that also are approved for a commercial indication helps to sustain availability of the product and improves healthcare provider familiarity with the drug. According to the dose reduction factor, the expected radiation protective effect of the radioprotector for humans is up to 1.5. The drug betaleukin (recombinant human IL-1β) proposed as agent of early urgent anti-radiation therapy applying within two hours after irradiation. A n announcement that the Department of Health and Human Services spent $290 million on a drug used to treat radiation sickness earlier this month raised eyebrows amid an uptick in nuclear threats ...The Biden regime is buying up $290 million in anti-radiation drugs for use in "nuclear emergencies" amid escalating tensions with Russia and heightened threats of a nuclear war. From Health and Human Services: FOR IMMEDIATE RELEASE. October 4, 2022. Contact HHS Press Office. 202-821-9446.WILMINGTON, Del., Dec. 13, 2022 /PRNewswire/ -- The global anti-radiation drugs market was valued at US$ 3.4 Bn in 2021 and is anticipated to grow at a CAGR of 9.9% from 2022 to 2031. Increase in ...Prussian blue traps radioactive cesium and thallium in the intestines to keep them from being absorbed by the body. These radioactive materials move through the intestines and pass out of the body (excrete) in bowel movements. Getting these materials out of the body help limit the amount of time they expose the body to radiation.These treatments include the following: Potassium iodide (ThyroShield, Iosat). This is a nonradioactive form of iodine. Iodine is essential for proper thyroid... Prussian blue (Radiogardase). This type of dye binds to particles of radioactive elements known as cesium and thallium. Diethylenetriamine ...Treatment for internal contamination. Potassium iodide (ThyroShield, Iosat). This is a nonradioactive form of iodine. Prussian blue (Radiogardase). This type of dye binds to particles of radioactive elements known as cesium and thallium. The radioactive particles are ... Diethylenetriamine ... Antineoplastic drugs used to shrink cancer cells before radiation therapy. Adjuvant chemotherapy. Chemotherapy administered after other treatments to shrink remaining cancer cells.Oct 6, 2022 · AP Photo, File. The U.S. Department of Health and Human Services (HHS) announced this week that the Biden administration agency has procured $290 million worth of a drug used to counter negative ... .

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